Day 1: Sunday, July 28th
12-1PM Lunch at Kingfisher
1:30-2:30PM Keynote Speaker: Sachdev Sidhu (U Toronto). Chair: Sarel Fleishman (Weizmann Institute)
2:30-3PM Coffee break
3-5:15PM Session 1: Structural Modeling. Chair: John Karanicolas (U Kansas)
- 3:00 Wojciech Potrzebowski (Lund): De novo structure inference of fibrilar protein structure using X-ray fiber difraction
- 3:30 Steffan Lindert (UC San Diego): Iterative molecular dynamics - ROSETTA protein structure refinement protocol can help overcome sampling limitations
- 3:50 Oliver Lange (Technical U of Munich): Automatic NOE assignment with ROSETTA
- 4:20 Brian Weitzner (Johns Hopkins U): Antibodies are proteins too!
- 4:40 Frank DiMaio (U Washington): High-resolution structures form low-resolution data
5:15-5:45PM Check into rooms, Setup Posters
5:45-7PM Dinner at Kingfisher
7:15-8:15PM Keynote Speaker: David Baker (U Washington).
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The three-helix bundle and beyond
8:15PM Poster session I, Beer, and Company
A special thanks to our sponsors:
Day 2: Monday, July 29th
7:30-9AM Breakfast at Kingfisher
9-10:30AM Small-group discussions
10:30-10:45AM Coffee break
10:45-12PM Session 2: Biomolecular Design I. Chair: Timothy Whitehead (Michigan State U)
- 10:45 Justin Siegel (UC Davis) and Ingrid Swanson Pultz (U Washington): Development of an oral therapeutic for Celiac disease
- 11:10 Eva-Maria Strauch (U Washington): Tetris of protein binding (not available for download)
- 11:35 Steven Lewis (U North Carolina): Structure-based design of an altered specificity antibody Fab interface enables expression of fully IgG bispecific antibodies (not available for download)
12:10-1:30PM Lunch at Kingfisher
1:30-3PM Session 3: Energy Functions. Chair: Sagar Khare (Rutgers U)
- 1:30 Jacob Bale (U Washington): Design of self-assembling two-component protein nanomaterials
- 2:00 Andrew Leaver-Fay (U North Carolina): Talaris overview
- 2:30 Chu Wang (Scripps): Computational design of organophosphate capture proteins using catalytic triads
3-3:30PM Coffee Break
3:30-5:30PM Session 4: Biomolecular Design II. Chair: Ora Schueler-Furman (Hebrew U)
- 3:30 Fabio Parmeggiani (U Washington): Design of repeat proteins: Larger structures from simpler topologies
- 4:00 Phil Bradley (Fred Hutchinson Cancer Research Center): Donut Design
- 4:20 Jacob Corn (Genentech): Keep a stiff upper loop: Altering conformation and dynamics at an interface (not available for download)
- 4:50 Yao-ming Huang (UC San Francisco): Computational design of small-molecule sensor/actuators
- 5:10 Jon Sack (UC Davis): State-dependent tarantula toxin binding to an ion channel voltage sensor
5:45-7PM Dinner at Kingfisher
7-8PM Keynote Speaker: Barry Honig (Columbia U). Chair: Oliver Lange (Technical U Munich)
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Structure-based prediction of protein-protein interactions on a genome wide scale
8:15PM Poster session II, Beer, and Company
Day 3: Tuesday, July 30th
7:30-9AM Breakfast at Kingfisher
9-10:30AM Small-group discussions
10:30-10:45AM Coffee break
10:45-12PM Small-group Presentations. Chair: Sarel Fleishman (Weizmann Institute)
12:10-1:30PM Lunch at Kingfisher
1:15PM Pictures
1:30-2:30PM Parallel Discussion Sessions
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ROSETTA Academy discussions
ROSETTA in Industry
Women in ROSETTA
Ad hoc meetings
3-5:30PM Parallel Session 5.1: ROSETTA Technology. Chair: Lior Limerman (Weizmann Institute)
- 3:00 Sergey Lyskov (Johns Hopkins U): ROSIE and testing updates
- 3:20 Firas Khatib (U Washington): FoldIt!
- 3:40 Jason Labonte & Michael Pacella (Johns Hopkins U): How to make the most of PyRosetta
- 4:00 Lior Limerman (Weizmann Institute): RosettaDiagrams: A graphical-user interface to ROSETTA programming
- 4:20 Daisuke Kuroda (Johns Hopkins U): Pushing the backbone in flexible docking
- 4:40 Noah Ollikainen (UC San Francisco): Computational re-design of enzyme substrate specificity using coupled side-chain backbone moves
- 5:00 TBA. Breaking News I. (Contact Oliver and Sarel during conference for placement of talk)
- 5:15 TBA. Breaking News II. (Contact Oliver and Sarel during conference for placement of talk)
3-5:30PM Parallel Session 5.2: ROSETTA Tutorials. Chair: TBA
- 3:00 Andrew Leaver-Fay (U North Carolina): Multi-state design
- 4:00 Steven Lewis (U North Carolina): ROSETTA is a cheeseburger OR The ROSETTA library structure for beginning programmers, FloppyTail Tutorial
5:45-7PM Dinner at Kingfisher
7:15-8PM Hike Organization
8-9PM PI Meeting
Day 4: Wednesday, July 31st
Bag lunch, checkout, and hike departures
The Rosetta Design Group thanks all Participants, the RosettaCommons Community, the University of Washington, and the Sleeping Lady Mountain Retreat for making this event possible. |
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About the Rosetta Design GroupThe Rosetta Design Group LLC was established in 2007 to bridge the gap between the RosettaCommons academic community and industry. |
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| Contract R&D in modeling and bioinformatics The Rosetta Design Group provides services ranging from assistance for computational scientists in protocol development to fully out-sourced R&D in structural modeing and bioinformatics for computational and experimental groups whose demands exceed their in-house capacities. |
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| Rosetta Design Group Website: http://www.rosettadesigngroup.com ROSETTA resources, events, jobs, the Macromolecular Modeling Blog™, and more. |
Industry Participants
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Randal Ketchem Amgen |
Walraj Gosal Isogenica |
Xavier Ambroggio Rosetta Design Group |
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Alexandre Zanghellini Arzeda |
Jacob Corn Yiyuan Yin Genentech |
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Vanita Sood EMD Serono |
Lei Jia |
Rene de Jong DSM Biotechnology Center |
Academic Participants
- RosettaCommons
- Baker Lab
UW - David Baker
- Rocco Moretti
- Christopher Bahl
- Per Greisen
- Stephanie Berger
- Eva-Maria Strauch
- Yifan Song
- Erik Procko
- Enrique Marcos
- Lei Shi
- Patrick Conway
- Hetu K
- Takahiro Kosugi
- Hahnbeom Park
- Christy Tinberg
- Fabio Parmeggiani
- Frank DiMaio
- Sinisa Bjelic
- Yakov Kipnis
- Keunwan Park
- Ingrid Swanson Pultz
- James Moody
- Firas Khatib
- David La
- Vikram K. Mulligan
- Austin Day
- Will Sheffler
- Jeremy Mills
- Jiayi Dou
- Yuan Liu
- Bonneau Lab
NYU - Richard Bonneau
- Doug Renfrew
- Evan Baugh
- Abba Leffler
- Kevin Drew
- Andrew Watkins
- Noah Youngs
- Riley Simmons-Edler
- Emily Koo
- Das Lab
Stanford CA - Rhiju Das
- Fang-Chieh Chou
- Joseph Yesselman
- Dunbrack Lab
FCCC - Jared Adolf-Bryfogle
- Maxim Shapovalov
- Mark Andrake
- Kortemme Lab
UCSF - Tanja Kortemme
- Amelie Stein
- Roland Pache
- Noah Ollikainen
- Kyle Barlow
- Yao-ming Huang
- Khare Lab
Rutgers U - Sagar Khare
- Beidi Lu
- Kenny Kostenbader
- Lu Yang
- Srinivas Annavarapu
- Kuhlman Lab
UNC - Brian Kuhlman
- Andrew Leaver-Fay
- Ryan Hallett
- Doonam Kim
- Tim Jacobs
- Joseph Harrison
- Kevin Houlihan
- Havranek Lab
Washington U - Jim Havranek
- Adam Joyce
- Ben Borgo
- Chi Zhang
- Roman Sloutsky
- Gray Lab
Johns Hopkins University - Jeff Gray
- Jason Labonte
- Sergey Lyskov
- Meiler Lab
Vanderbilt University - Jens Meiler
- Steven Combs
- Sandeep Kothiwale
- Gordon Lemmon
- David Nannemann
- Stephanie DeLuca
- Sam DeLuca
- Amanda Duran
- Jessica Finn
- Darwin Fu
- Elizabeth Nguyen
- Fleishman Lab
Weizmann Institute of Science - Sarel
- Gabi
- Ravit
- Adi
- Christoffer
- Assaf Alon
- Lior Zimmerman
- Furman Lab
Hebrew University - Ora Schueler-Furman
- Orly
- Nawsad Alam
- Lange Lab
TU M�nchen - Oliver Lange
- Justin Porter
- he Zhang
- aiyong Zhang
- atjana Braun
- Richardson Lab
Duke University - Steven Lewis
- Yarov-Yarovoy Lab
UC Davis - Vladimir Yarov-Yarovoy
- Jon Sack
- Drew Tilley
- Phuong Tran Nguyen
- Fan Yang
- Gaurav Bhardwaj
- Schief Lab
Scripps Research Institute - Name
- Bill Schief
- Dan Kulp
- Shantanu Bhattacharyya
- Joseph Jardine
- Rosetta Design Group
- Xavier Ambroggio
- Karanicolas Lab
KU - John Karanicolas
- Jimmy Budiardjo
- Ragul Gowthaman
- Andrea Bazzoli
- Yan Xia
- Siegel Lab
UC Davis - Justin Siegel
- Steve Bertolani
- Derek Decker
- Terry O'Brien
- Katie Guggenheim
- Wilson Mak
- Strauss Lab
Los Alamos National Lab - Charlie Strauss
- Hossein Fazelinia
- Novus Estudio
- Bax Lab
NIH - Nikolaos Sgourakis
- Malmstroem Lab
ETH Zurich - Lars Malmstroem
- George Rosenberger
- Marija Buljan
- Abdullah Kahraman
- Whitehead Lab
Michigan State - Tim Whitehead
- Justin Klesmith
- Jim Stapleton
- Caitlin Kowalsky
- National Renewable Energy Lab
- Deanne Sammond
- Ingemar Andre Lab
- Ingemar Andre
- Sebastian R�misch
- Robert Lizatovic
- Wojciech Potrzebowski
- RosettaCommons Guests
- Sachdev Sidhu (U Toronto)
- Barry Honig (Columbia U)
- Steffen Lindert (UCSD)
- Joseph Plaks (UC Boulder)
- Florian Richter (Humboldt U)
- Luki Goldschmidt (UCLA)
- Sen Liu (China Three Gorges U)
- Chu Wang (Scripps)
- Jenny Hu (UCSF)
- Colin Smith (Max Planck)
- Andrew Morin (Harvard, SBGrid)