Macromolecular Modeling Blog ™

Keen observers and avid followers of this blog must have noticed the dwindle if not complete lack of posts in the past 3-4 months. The main reason for this drought was my personal and professional transition. I have completed my Ph.D. studies (on peptide-protein interactions) at the Furman Lab (The Hebrew University, Jerusalem, Israel) and took a position as a post-doctoral fellow at the Schoichet Lab (University of California, San Francisco) in the field of structure based virtual screening of small molecules with a touch of Chemoinformatics.

The move, the acclimation to California and to a new research area, have left little to no time for writing, but now as the dust settles, I hope to find time now and then to share interesting papers, opinions and news. I imagine this change in research area will reflect in future content, and am sure you’ll find it as fascinating as I do.

Looking forwards to see what the future holds…

Last month in Nature Chemical Biology, Dan Mandell and Tanja Kortemme from UCSF published a great review of current research in macromolecular modeling and experimentation: Computer-aided design of functional protein interactions. The review focuses on protein-protein interactions and interfaces but also covers the general field of macromolecular modeling in some depth. It includes sections that introduce basic concepts in modeling and tables that provide a succinct snapshot of recent accomplishments and how they tie in to the greater field.

Having finished reviewing a review, I will be following Borges’ lead and review papers from the literature that have not yet been written. Any paper suggestions?