The 1000th structure – PDB ID 2xml – belongs to JmjD2C, a protein involved in epigenetic signalling. JmjD2C is known to play a key a role in the maintenance of self renewal in stem cells as well as roles in cancer.
I'm the 1000'th structure solved by the SGC. PDB id 2XML
The SGC (a public-private partnership created to place 3D structures of proteins of medical relevance into the public domain) have been able to take the original research articles published in the Collection and create ‘enhanced’ versions of them. As a result each of the research articles is now also available as an ‘interactive’ version, incorporating user manipulable, three-dimensional molecular structures.
Readers of these enhanced articles first need to download a plug-in for their browser but are then able to click on hyperlinked text within the article to ‘fly’ to the relevant position within the molecule, and to interact with it at will (by zooming, rotating, animating, and exploring). The seamless integration of interactive 3D structures into the actual text of the article provides considerable new functionality for readers, and it is hoped it will lead to new insights and discoveries.
This technology is simmilar to the Proteopedia ongoing project which enables the annotation of structural data with online animation using the wiki and Jmol frameworks.
It seems that the prevalence of both methods would only go as far as the authors of newly published papers would invest time to create these beatiful, educating animations.
