Jun
08
2011
2

One Sided De-Novo Computational Design of a Protein-Protein Interaction

In a recent Science paper, Sarel Fleishman et al. report the de-novo computational design of a protein interface to specifically target and tightly bind a surface patch of the flu hemaglutinin protein. We interview Sarel to get the insights from behind the scenes and the outlook for this exciting approach.

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Jan
31
2009
0

Bi-Weekly Digest 31/01/09

In this Bi-Weekly Digest, several folding theory papers and a first look at a large ribonucleoprotein particle which may play a role in pathogen clearance. 

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Nov
08
2008
0

Bi-Weekly Digest 08/11/08

In this Bi-Weekly digest – relevant titles form current issues of molecular and computational biology literature, amongst featured titles: Surface Sites for Engineering Allosteric Control in Proteins and The RNA Polymerase ”Switch Region” Is a Target for Inhibitors. If you want to initiate in a public discussion on one of these, let us know in the comments.

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