Feb
22
2017
0

Only TWO spots left for RosettaCON2017!

RosettaCON2017_edit_slide

There are only TWO spots remaining for RosettaCON2017 for members of the pharmaceutical, biotech, and related industries. Request an invitation through the RosettaCON website.

RosettaCON2017 dates: August 8 – August 11, 2017.

RosettaCON is an annual conference at the Sleeping Lady Mountain Retreat in Washington’s Cascade Mountains, where Rosetta Commons member laboratories share the latest experimental and computational research breakthroughs in protein and macromolecular engineering and structure prediction . The Commons grew out of David Baker’s laboratory at the University of Washington and is now a consortium of over forty international laboratories. Rich Bonneau of New York University, Charlie Strauss of the Los Alamos National Laboratory, Bruno Correia of EPFL of Lausanne, and Vladimir Yarov-Yarovoy of the University of California at Davis organize this year’s conference. We are delighted to have Ian Wilson of The Scripps Research Institute, and Shoshana Wodak of the Vlaamse Institute of Technology (VIB) and the Vrije Universiteit Brussels (VUB) as confirmed guest speakers.

This year’s conference will be featured in a special addition of PLoS. All attendees are invited to contribute to the special edition.

In addition to showcasing cutting edge research, there will be an industry-focused session for fostering collaborations and exploring the exchange of ideas, people and resources. We invite you to participate in this session through presentations, flip charts, and breakout discussions. We hope to expand on the ever-growing number of industry-Rosetta Commons collaborations.

Apr
08
2015
1

Request an invitation to RosettaCON2015

Requests are now being accepted through the RosettaCON website for invitations for the limited openings for RosettaCON2015 for members of the pharmaceutical, biotech, and related industries.

RosettaCon is an invitation-only conference at the Sleeping Lady Mountain Retreat in Washington’s Cascade Mountains, where Rosetta Commons member laboratories share the latest experimental and computational research breakthroughs in protein and macromolecular engineering and structure prediction. The Commons grew out of David Baker’s laboratory at the University of Washington and is now a consortium of twenty-four international laboratories. Justin Siegel of the University of California at Davis and Frank DiMaio of the University of Washington organize this year’s conference. We are delighted to have Bill DeGrado of the University of California at San Francisco, Roberto Chica of the University of Ottowa, Lillian Chong of the University of Pittsburgh, and Gaël McGill of Digizyme and Harvard Medical School as confirmed invited guest speakers.

In addition to showcasing cutting edge research, there will be an industry-focused session for fostering collaborations and exploring the exchange of ideas, people and resources. We invite you to participate in this session through presentations, flip charts, and breakout discussions. We hope to expand on the growing number of industry-Rosetta Commons collaborations, such as:

  • Jeffrey Gray lab – AxioMx collaboration deciphering the specificity of antibodies binding phosporylated peptides
  • Jens Meiler lab – Eli Lilly collaboration developing methods for drug design
  • Tanja Kortemme lab –DSM collaboration developing ROSETTA applications to re-design enzyme substrate specificity

Hands-on Rosetta tutorial sessions may be offered for industry attendees interested in learning to use ROSETTA.

After the conference, hikes, climbs, and backing trips are organized by conference attendees on the most scenic trails and stellar climbs in all of Washington State.

 

May
15
2014
0

Two spots remaining for RosettaCon2014!

There are two spots remaining for RosettaCon2014 this summer, July 30th – August 2nd! RosettaCon is the annual meeting of members of the Rosetta Commons and scientists using Rosetta in the pharmaceutical and biotechnology sectors. There will be workshops, seminars, and a special industry collaboration session. The conference will take place at the beautiful Sleeping Lady Mountain Retreat in Leavenworth, Washington, about 2.5 hours outside Seattle in the dramatic Cascade mountain range. Kick back, have a beer, fold a protein, re-design a protein, and go for a hike.

Please email info@rosettadesigngroup.com for more information and registration details.

Feb
05
2011
0

Rosetta 3.2 Released

Rosetta 3.2 is the first rosetta release in over a year and is chock-full of new features. Get your (free for academia) copy at: www.rosettacommons.org/software and find the new and improved documentation at: www.rosettacommons.org/manuals/archive/rosetta3.2_user_guide

What’s new in Rosetta 3.2 ?

“Automatic” Comparative Modeling: build structural models of proteins using one or more known structures as templates for modeling.

Flexible Peptide Docking: create high-resolution models of complexes between flexible peptides and globular proteins, starting from approximate, coarse-grain models.

Symmetric Docking: predict the structure of symmetric homooligomeric protein assemblies starting from the structure of a single subunit. The relative subunit orientation and conformations of side-chains are simultaneously optimized for a symmetric protein assembly.

RosettaMatch Application: search through a protein backbone (“scaffold”) to find positions where a binding site for a desired small molecule (or biomolecule, in the more general case) target can be introduced.

Molecular Replacement: solve difficult molecular replacement problems. It will generally be used alongside the molecular replacement software Phaser.

Sequence Tolerance: perform specificity prediction and library design (i.e. for phage display, yeast display, or other selection techniques).

Written by admin in: News,Resources | Tags: , ,
May
20
2009
4

Pfizer using RosettaDock on the Amazon Cloud

In a post yesterday on the Bleeding Edge Biotech Blog, Adam Kraut gives an expanded version of his article for Bio-IT World entitled Antibody Docking on the Amazon Cloud describing how Pfizer is leveraging the power and flexibility of cloud computing to run antibody docking simulations using Rosetta. Pfizer with help from the Rosetta Design Group (that’s us) developed an antibody modeling and docking workflow, which they then scaled up and tested on the cloud with help from BioTeam (which Kraut consults for and talks about in his post). This is a fascinating article and certainly the Pfizer/RDG/BioTeam/Rosetta/Amazon synergy is a phenomenon on the bleeding edge.

Nov
21
2008
1

RosettaCon 2009

Disclaimer: We at “Rosetta Design Group“, use, develop and love Rosetta. That being said, you’d understand our amicable descriptions.

Rosetta is a modeling software suite that can do anything that have to do with modeling. From ab-initio folding and homology modeling, through protein-protein or protein-ligand docking, and to protein and enzyme design. Dozens of papers were written about its different protocols and about their application to specific biological systems. The secret for Rosetta’s success are the Rosetta Commons: a consortium, including over a hundred scientists from over 12 Universities which continues the ongoing research and development of the software.

Every summer the Rosetta Commons researchers, world experts on macromolecular modeling, as well as the people behind the code, gather at the Rosetta Conference (dubbed “RosettaCon”) to exchange ideas and discuss future plans.

We would like to invite you to RosettaCon to participate in workshops, seminars, and to have an opportunity to meet the Rosetta Commons researchers.
RosettaCon will take place during August 4-7 at the beautiful Sleeping Lady Mountain Retreat in Leavenworth, Washington, about 2.5 hours outside Seattle, set amid towering conifers and dramatic mountain scenery.

The Rosetta software is currently licensed for free to users at academic and nonprofit institutions and have over 2000 academic users in more than 32 countries. Commercial entities can use Rosetta by paying a license fee. Amongst past participants in these workshops are representatives of the big pharma companies and Rosetta’s licensees, RosettaCon Workshop 2008 was sponsored by Merck and Nanorex.

If you may be interested in joining us this year, please let me know, We will be sending the preliminary agenda to assess participants preferences in terms of workshop session contents and seminar topics, and to taylor them to your needs.

For more information and registration, email:

nir AT rosettadesigngroup.com

Written by Nir London in: Events | Tags: , , , ,

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