Macromolecular Modeling Blog ™

In a recent review published in Biochemistry, Kaufmann, Lemmon and DeLuca et al. from the Meiler Lab, cover the Rosetta modeling suite capabilities. More importantly, as supplementary information they provide tutorials to demonstrate 6 basic use cases of Rosetta.

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Amelie Stein, Roland A Pache, Pau Bernadó, Miquel Pons, Patrick Aloy (FEBS Journal, 2009)

This recent mini-review by Stein et al. focuses on the mechanisms that enable dynamic, transient, short lived interactions in cellular networks. Of special interest are the always popular “motif recognition domain”-”short flexible peptide” interactions. However, post translational modifications and regulation by disorder are also discussed. We concise the review further to some basic/interesting/anecdotal/”pondering worthy” points.

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