Macromolecular Modeling Blog ™

A meeting for everyone that liked this post (17 Protein disorder prediction servers):

Dates: 4-6 October, 2010

Venue: Institut d’Estudis Catalans, Barcelona, Spain.

Registration deadline: July 15, 2010.

There is no registration fee for this conference, but the number of participants is limited.

Organizers:

• Miquel Pons and Pau Bernadó (IRB Barcelona)
• Peter Wright (Scripps Research Institute, La Jolla, USA)

Speakers:

• Patrick Aloy, Institute for Research in Biomedicine. Barcelona (SPAIN)
• Toshio Ando, Kanazawa University (JAPAN)
• M. Madan Babu, MRC-Laboratory of Molecular Biology. Cambridge (UK)
• Doug Barrick, Johns Hopkins University. Baltimore (USA)
• Martin Blackledge, Institut de Biologie Structurale Jean-Pierre Ebel. Grenoble (FRANCE)
• Ashok Deniz, The Scripps Research Institute. La Jolla (USA)
• Chris Dobson, University of Cambridge (UK)
• Jane Dyson, The Scripps Research Institute. La Jolla (USA)
• Keith Dunker, Center for Computational Biology and Bioinformatics. Indiana University (USA)
• Julie Forman-Kay, University of Toronto (CANADA)
• Vince Hilser, The University of Texas Medical Branch (USA)
• Richard Kriwacki, St. Jude Children’s Research Hospital. Memphis (USA)
• Sonia Longhi, Université d’Aix-Marseille (FRANCE)
• Eckhard Mandelkow, Max-Planck unit for Structural Molecular Biology. Hamburg (GERMANY)
• Dmitri Svergun, EMBL-Hamburg Outstation (GERMANY)
• Peter Tompa, Institute of Enzymology, Hungarian Academy of Sciences. (HUNGARY)
• Vladimir Uversky, Center for Computational Biology and Bioinformatics. Indiana University (USA)
• Markus Zweckstetter, Max-Planck Institute for Biophysical Chemistry. Göttingen (GERMANY)

Intrinsically disordered proteins are Nature’s response to the increased complexity of higher organisms and are associated with diseases such as cancer and neurodegeneration. Genome sequencing projects and bioinformatics analyses have shown that disordered proteins are highly abundant in eukaryotes and are tightly regulated. Enabling technologies that offer structural information in solution, such as Nuclear Magnetic Resonance, Small Angle X-ray scattering, and single molecule fluorescence, are providing novel insights into the structural propensities and interactions of disordered proteins. A new paradigm, in which dynamic averaging of conformational ensembles is central, is emerging for the structural and functional analysis of disordered proteins.

For more information visit the IRB’s meeting website.