Partners

Xavier Ambroggio Nir London
Xavier Ambroggio Nir London
 

Advisory Board

David Baker
David Baker
Jeffrey Gray
Brian Kuhlman

Ora Furman-Schueler

Gabrielle Campbell
Scientific Advisory Board
Business Adviser
 

Select Clients

 

In the Literature

ROSETTA related:


London N, Ambroggio X. An accurate binding interaction model in de novo computational protein design of interactions: If you build it, they will bind. J Struct Biol. 2013 Apr 1.

Leaver-Fay A, Tyka M, Lewis SM, Lange OF, Thompson J, Jacak R, Kaufman K, Renfrew PD, Smith CA, Sheffler W, Davis IW, Cooper S, Treuille A, Mandell DJ, Richter F, Ban YE, Fleishman SJ, Corn JE, Kim DE, Lyskov S, Berrondo M, Mentzer S, Popovi? Z, Havranek JJ, Karanicolas J, Das R, Meiler J, Kortemme T, Gray JJ, Kuhlman B, Baker D, Bradley P. ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules. Methods Enzymol. 2011;487:545-74.

Acknowledgement for work with Arana Therapeutics:


Clarke AW, Poulton L, Wai HY, Walker SA, Victor SD, Domagala T, Mraovic D, Butt D, Shewmaker N, Jennings P, Doyle AG. A novel class of anti-IL-12p40 antibodies: Potent neutralization via inhibition of IL-12-IL-12Rbeta2 and IL-23-IL-23R. MAbs. 2010 Sep 20;2(5).

Collaboration with the Tezcan Lab at UCSD:


Brodin JD, Ambroggio XI, Tang C, Parent KN, Bakers TS, Tezcan FA. Metal-directed, chemically tunable assembly of one-, two-, and three-dimensional crystalline protein arrays. Nature Chem. Mar 2012; doi:10.1038/nchem.1290



Brodin JD, Medina-Morales A, Ni T, Salgado EN, Ambroggio XI, Tezcan FA. Evolution of metal selectivity in templated protein interfaces. J Am Chem Soc. 2010 Jun 30;132(25):8610-7.

 

Awards


Member Awards: National Science Foundation, National Institutes of Health, Gordon and Betty Moore Foundation, Helen G. and Arthur McCallum Foundation

Advisor Awards: National Academy of Sciences, National Science Foundation, National Institutes of Health, Robert Bosch Foundation, Beckman Foundation, American Association for the Advancement of Science, Howard Hughes Medical Institute, Foresight Nanotech Institute, Searle Scholars Program, IBM, American Chemical Society, Gigatrend, Packard Foundation, Protein Society